Critical Article Review 2

Author(s): Andrew R Hart

Description

Three articles have been reviewed. They are related to faecal occult blood testing and its role in the morbidity and mortality from colorectal cancer.

1. Mandel JS, Bond JH, Church TR, Snover DC, Bradley GM,Schuman LM, Ederer F.
Reducing mortality from colorectal cancer by screening for fecal occult blood.
N Engl J Med 1993; 328: 1365-71.

Objectives and methods
This American study was the first randomised controlled trial to report a reduction in mortality from colorectal cancer in those completing faecal occult blood tests. The study was conducted amongst 46 500 volunteers aged 50 to 80 years old connected to the American Cancer Society.