Description
Patients with chronic liver disease are prone to developing
hepatic encephalopathy, a complex neuropsychiatric syndrome
with multifactorial aetiology. Hepatic encephalopathy is
associated with poor prognosis and has a negative impact
on health-related quality of life. Several therapies have
been tested in clinical trials but strong evidence supporting
the routine clinical use of any specific therapy is currently
lacking. Further clinical trials evaluating treatment
modalities targeting specific pathophysiologic mechanisms
implicated in hepatic encephalopathy are needed.
