Role of Mohs surgery in the management of skin cancer

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Abstract

Mohs micrographic surgery is a microscopically controlled method of skin cancer excision which minimises recurrence rates and maximises conservation of surrounding normal tissue. Micrographic surgery using horizontal frozen sections has achieved wide acceptance as the optimal treatment for those basal cell carcinomas and squamous cell carcinomas that fulfil particular characteristics. These include recurrent or incompletely excised tumours, those on particular areas of the face and those with clinical and histological features associated with a higher probability of incomplete excision if conventional methods are used. Mohs surgery using either frozen sections (with or without immunohistochemistry) or horizontal paraffin-embedded sections, has also been adapted to the excision of skin tumours including certain squamous cell carcinomas, dermatofibrosarcoma protuberans and lentigo maligna.