Description
Fronto-temporal dementia (FTD) is the second most common cause of dementia, after Alzheimer’s disease (AD), in those aged less than 65 years. FTD presents with early personality changes, social disintegration or language problems. Clinically, three distinct disease entities can be distinguished; frontotemporal dementia, progressive nonfluent aphasia and semantic dementia. These distinct clinical syndromes are determined by the distribution of neurodegenerative changes in the brain. A positive family history is common and can be present in up to half the patients with FTD. Like other degenerative dementias the onset is gradual and the course slowly progressive, with as yet no curative treatment
