Description
Therapeutic drug monitoring (TDM) has an important role
in certain areas of therapeutics such as anticonvulsant and
antibiotic therapy, therapy with antidepressants and chemotherapeutic
agents and some drugs acting on the heart, respiratory and
immune systems. However, it is important to establish the
need for such monitoring, and to use plasma drug measurements
properly if the true benefits of TDM are to be realized. This
article discusses the general principles applicable to TDM
and illustrates them with reference to antiepileptic drugs.
