Description

Polycystic Ovarian Syndrome (PCOS) is a
common disorder with clinical manifestations of
anovulatory infertility and hyperandrogenism with
oligomenorrhea/amenorrhoea, hirsuitism and acne.
There is a higher prevalence of obesity, impaired
glucose tolerance, type2 diabetes,
hyperinsulinaemia and adverse cardiovascular
profile in these patients. The complicated interplay
between genetic factors, abdominal obesity and
insulin resistance play a key role in
pathophysiology. Management should be tailored
to individual needs. The understanding of the
principles of management of long term implications
aids to offer holistic approach to this disorder.
Many different therapies may be offered to regulate
menstrual cycle, induce ovulation and improve
signs of hyperandrogenism. Lifestyle improvement
and weight reduction are the most important
predictors of long term health.
This article is aimed to guide general practice
especially emphasising the long term management,
evidence for use of various therapies and points of
referral to specialist.