Description
Unstable angina is a common presentation of acute coronary syndrome that can progress to acute total coronary occlusion and subsequent myocardial infarction. Patients with unstable angina comprise a heterogeneous group with varying degrees of risk of progression to acute coronary occlusion. Identifying the higher risk group involves a detailed clinical history, electrocardiograph examination, biochemical markers of myocardial injury and contrast angiography.
Therapies directed at preventing each of its pathophysiological mechanisms are the cornerstones in halting its progression. These include antiplatelet, antithrombotic and vasodilatation pharmaceutical therapy as well as mechanical intervention such as angioplasty and coronary stenting. This paper looks at the evidence which on current best therapies are based.
