A case of haemophagocytic syndrome in HIV-associated disseminated histoplasmosis

£25.00

Author(s): Dr Nidhi Vaid & Dr Parind Patel

Description

Disseminated histoplasmosis is an opportunistic infection
which is commonly associated with HIV. Haemophagocytic
lymphohistiocytosis (HLH) has been described as a
secondary phenomenon to infection, collagen vascular
disorders and malignancies. In patients with HIV, cases of
reactive haemophagocytic syndrome associated with
disseminated histoplasmosis have been reported with CD4
counts of less than 50 cells/μl (450-1660 cells/μl). We
report a case of a 25 year old man with HIV who presented
with a CD4 count of 153 cells/μl and would suggest that
this diagnosis should be considered at higher CD4 counts
than previously reported.