Description
With continued improvement in survival from childhood cancer, such that 70% of patients are now long-term survivors, attention has focused on the lasting morbidity associated with the disease itself and it’s successful treatment. Both radiation and chemotherapy may have long-term effects on the endocrine system with thyroid dysfunction, infertility and poor growth all well described. The challenge for oncologists today is to minimise late toxicity without compromising the excellent survival rates. In this review we concentrate on growth and endocrine dysfunction following treatment for childhood cancer.
